I suppose it may be a like a lot of things. Moderation is probably the key. Also, I think a lot of may come down to what side you are reading. Naturalists love it, the medical profession hates it (for obvious and various reasons I suppose) I have read more positives than negatives though.
I guess for me, it comes down to talk to people who have actually went through it and get their opinion - especially like Ellsrider and find out both the negatives and positives. For me, when I did the detox thing, I didn't notice weight loss as much as I just felt better. More energy and less 'bound' up.
just my .02 FWIW