No tubes is definently the way to go. Lower pressure and less flats for sure, weight depends on your set up. Although others have spoken against using standard tires (non ust), I and many others have had great luck. A ust tire is sealed and has a bead that is more heavy duty, which will be easier to get inflated, sealed and is less likely to blow off the rim in intense aplication. The penalty is extra wieght and the expense of new tires. Stans has a list on their site of tire brands that work beter than others. If you have one of these types you enjoy riding in your quiver, it is worth a try. Your first try at this will be messy, and time consuming... watch the video on the stans site and follow exactly, it will work. Then test ride in the neighborhood, when the tires will hold air over night try them on the trail and take 2 tubes. If you are a fairly light rider (180 or less) and are tend to keep the bike on the ground most of the time you should be just fine. Clydes and huckers go directly to ust. Somewhere in the middle are "tubeless ready" tires that have heavy duty beads yet still require sealant = light and no blowouts. Take a look at specialized "The Captain tubliss" as a good example that works quite well I hear.