Happened to me, too. Hubby didn't bungy them down properly (I will blame him since I was in the restroom at the time.)
Fortunately, it was just the older hybrid Giant that I started out with off road...my friend had paid $10 for it in a thrift store (her words, 'I think Giant's supposed to be a good brand') and I invested another $50 at LBS (unnamed, and after a few times of trying to be supportive, never visited again.)
We had just turned out of TC and it happened right by the interstate exit. Older bike, steel frame, hardly any damage.
But yes, it can happen to anyone.
I so love my RAV4. We fit 3 bikes in the interior, and 3 peeps, heading up to Croom this past Sunday. All 3 bikes fit in without a problem, front wheels off, upright, bungied together.
Jim (what's his last name??? the Macgyver guy) has an elegant set up in the interior of his Honda Element. IMHO, if you can transport your bike inside your vehicle you're better off.